?? ???????|?????,“??”???????
????:1????????:?????
2???????
3???????
4???????
5??????????????
?????????????????????,????CAR-T(???T?)???????“?”???
CAR-T??????????????,????:?????,????????“?????????????????”?“?????????????????,??”?????????????????,????????,???????????
?????“???????????”,??????????
?????????? 11 ?,?????????????????????,99.9??CAR-T??,?????????????CAR-T??????????????????1??,??????????CAR-T??????????,?????,????????120??????????????????????CAR-T?????????????????????60????????????????
8???,?????,??CAR-T?????6?????CAR-T???“???????????”????,?????????,????????“??????????”???,????????????“???”???????“????????????”??????,???
????,????????:????????“????????”?????????“?????????”???????????????????,??CAR-T???????“????”????????,??????????????????
????????,????????????“????”????????,?????????,CAR-T???,??????????????????????????
?????????
?70%?????????????60%????,?????“??????????????”???????????41.3%?
??????,????????????????????????,???????????????“????”???????????,??,????“?????????”,?,????????
??CAR-T????,“??????????”????????
?????????®(?????????????)??,???????2021???,??????????????,??????????????????,????????????????????
???????“?????????????????????”????,??8?????????????,???????????,?????????????????????/????,????????????????????,?????4??????????CAR-T????????????????
??,???????,??29????????,?????30????????????????????????,??????????????99.9?????????????????????????????????????/?????~120???/???????CAR-T???,?????????
?????4?,???????????????,??????????????????,??,?????,??CAR-T????????????,???????????????????CAR-T????????????
??,CAR-T??????,????????????????????“???????”,???????????????“??”??????????,???CAR-T???????????????????????,???????????
???????????????????????????,??????????,???
?????????«??????»???????,???????,??“????”??????????????,??“?????”?????????????,????????????
?????????,CAR-T????????,?????????????:
?????????,CAR-T???????100??,?????“??”????????????2023???????????1.9????(19.4%)??1.7??????????(25.3%),???????????????????????????????????,??“??”????????????????????,????????????????????“????????????30???????”?????,????????????????“??????????????”?
?,???,??,????,???????????????????CAR-T???,??,??,????????????????????????,??????????????????“???????”?????????????????????????
??????????????
??,????????????CAR-T?????????????,??“??????????????????????????,?”???,?“????????”????
??,?????????????????????????????????????????,??CAR-T??????,????????????
???????1?,?????????“??”,??????????????,???????60??
??????????????????????????2024??,????????????????,?????,?????????????????????????????,?????,??????????
?????????????????????????:“????,???????????????,????”
????????????????????????,??????,????????????????????,????????“???????”,?????????????????????????????????????,???????????????????????,????,????????,???,??????????????????????????????,?????
??,????“1+3+N”??????????,??“N”???????,???????????,???“N”???????,???????????????
?????????????????,??????????????????
???????????????????????????“?????????????”?,??????????????,?????????
????????,??,????,??????,???????????????
“????,???????300??????????????????,?????????????????CAR-T??,CAR-T????????????????????????????????,????,???????,??‘????’?,????????????????????????????,??,????????????????????,???????????,?????,????????;??????????????,?????????????????????,???????,????????‘????????’?”????
????“?????????????”??????????,???????????????????,???????????????????
????????????????,???????????,????????????????????????????????,????????????????,??????????????,????50??????,??????????,?,????????????????????
????????,?????,?,????????????,??????????????????????
???????????,???????????????,??????????????????????????????????,??????“?????????”,??????????????,??????????????????????????????????,??????????????
????????????,???????????????????????,??,??????
????“???????”,???,?????????????????
????100???CAR-T?????,????????,??????,????????????????,?CAR-T???26???,??,???????????????4?????????????,???????
??“??????????”,??????????,??????,??????????
“??100??????????,????CAR-T???????????????????????????,??????????,?????????????????????????????????????,??????????????????,?????????????????????”???????????,????????,????????????????;???????????????;??,??,???
CAR-T????????????????
????CAR-T??????????,????:CAR-T??????????????????CAR-T?????????
???CAR-T???????????????????,???????????,???????????,??????CAR-T??????????????????????????,????????????????????,??????????????????????
????????,??????“??”????????????????,????????????????????,????,????????????“???????????”?????????????,???????,???????????????????CAR-T??,????????????,??????????
?????????????,CAR-T??????,???DRG/DIP???????,????“?????”?????????,?????????????“???,????????,???”???
???????????,“???????????????”??????????,?????????“????????”??????????????????????????????????,?????CAR-T????????
“????????CAR-T?????????????????50%~70%?????????????”????CAR-T???????????????????????
???,???CAR-T???????,???????????,????????????,????????CAR-T???4.3????????,??CAR-T??
???????????,?????,CAR-T??????????,???,???????????CAR-T????????????
????CAR-T?????,????PD-1??,CAR-T???,??,???????,?????,??,?????????????????,????
??????????2024?????3????1????????????CAR-T??(????????????????)???????,????? CAR-T?????????????11 ??????????,???????6???????
???“2025-2030????????(CGT)??”??,??????????,?????????????????CAR-T?????????????????????,2023???20%,?????????????184??????,???????168??????????????????????????????????????
??????????,????????????????????,??????CAR-T???“??????????”???????????
???????,2032?????????CAR-T???????????885.2???????????????????,????“??????,???????????”(?????? ????:????????????????) ????????????????:???????