??????????????????????

????:??????:??????????

??7????????????????3??????????? (??????? ???????)?????????????????????????????3??,???

???(????)??????HBV???????????(siHBV),??,?????

??Signal Transduction and Targeted Therapy?

???????????????????,?????(HBV)??(CHB)?????????,???????(RNAi)??(HBsAg)??????????????

??????????,??(tLNP)???????????,?????????????????????????????????,????????????????????????????????,???RNAi????????????????HBV??????????????????,??????,????????HBV??????????T?,???(????) ??????????????????????????????????????:??????????????????