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?????,???????????????,??????“?????????????”?????1950????????????????????????????(????cAMP?cGMP)?,??????,????????,?????????????????????,?????????????,?????????????????????KomA(??????A)?KomB(?B)?KomC(???????C)??????????????????????,???(DNK)????“??”:KomA???????????????????????DNK?????????????,??????????????????(dAMP)?dITP???KomC????????????????NAD⁺,????????????????????“??”??????????????,?????????????????,??????????“??????????????????”???????????,?????????????????????????????????????“???????????????”??????,???

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