?? ?????|???????,“??”???????
????:1????????:??????????
2??????????
3?????????????
4?????????
5????????
???????????,???????CAR-T(??T????????)??????????????????????“???????”???????????????
CAR-T????,?????????:?????????????????????,????????“?”????????????????“???,????”??,?????????????????????,????????????
???????????????“???????????”,????????????????????
? 11 ??????????,???????,99.9????CAR-T??????????????,??CAR-T?????????????????????????1???,??????CAR-T??,??,????????????????????????120???????????????CAR-T??60????????
8??,??????,??????????CAR-T???????6???????????????????CAR-T??“???”?????????????,??,??“???????????????????”???,??????????????“?????”????????“?????????”??,???????
???????????????????????,???????:???“??”???????“??”??????????????,???CAR-T??????????????“????”??????????,??????
????????????,?????“?”?????????????????,???????????????????????????????,CAR-T????????,??????
????????????????????????
????????70%??????????60%???,????????????“????”???41.3%?
??,?????????????????????,???????“??????????????????????????”????,??????,?????????“????????????????”,?????,???
???CAR-T?????,“???”?????????????????????????????
??????®(??)????,??????????2021????,?????,????????????????,?????
?????????????????????“?????????????”????????,???????????8????????????????,????????????,???/??????????,?????????????????????????????????????,??4??????????????????CAR-T???????
??????,???,??29???,??30?????????????????????????,?99.9???????/??~120??????/?????????????????CAR-T??????????,??????????
??????????4??????????,??????????,??????????????,??,?????????????????????,???CAR-T???,??CAR-T??????
????????,CAR-T??,???“?????”,??“??????????”???????,???????????????????CAR-T?????????????,??
????????????,???????,??????
?«??????????»????,??????????,?“??”??????,????“???????????”??,???????????????
??,CAR-T??????,???????:
?????????,CAR-T?????????????100???????,??????????“???????????”???2023????????????????1.9????????(19.4%)????????????????1.7??????(25.3%),???????????????,??“???????????”?????????????????????????????????,???????????????“??????????????30???????”????????????,?????????????“??”?
??,???,??????,???????????,??????CAR-T??????,????????????,???????,??????????,??“?????”???????????????????
???????????????
?????????????????????????,??????????CAR-T????????????,????????“??????????????????,????”????????????,???????????????“?????”???????????????????????????????
???????,????????????????????????????????????????????????????,???????????CAR-T???????????,?????????
??1????????,?????????????????????“???”,????,???????????60??????
??????????2024??????????????????,??,?????????,??????????,???,??????????????
??????:“??????????,?,????????????”
??????????????????,????,?????????,?????????????????“????????”,?????????,????????????,?,???,????,??????????????????,??
??,????????????????????“1+3+N”??????,??????????“N”???????????????,????????,?????“N”????????????,????????????
???????????,?????????????
??????“??”??????????????????????????,?????,????????????
?????????,??,?????????????,?????????????????,????????????
“?????????????????,??????????300????????,?????????????CAR-T??????,CAR-T?????????????????????,????,??????,????????‘?????’????????,?????????,?????????????,????,?????????????????,???,?;????,????????????????????????,???,????????‘??’?”???????????
?????????????“?????”??????,?????????????,??????????????????
?????,?,??????????????????????????????????????????????????????????????,????,??????????????????????,?????50??????,???,??????????,?????????????
???,???????,????,???????????????????????????????????,?????????
???????????,????????????????????,??????????????????,???????????“????????????????”,?,???????????????????????????????????????,???
??????????????,????????,?????,??
?????????“??????????????????”,????????,????????????????
??????????????100???????????????????????????CAR-T??,???????????????????????????,????????,?????????????????,??????????CAR-T??????????26????????????,????????,????????????4?????????,??????????
??“??????????”,?,????????????????,????????
“???????????100???????????????,??CAR-T??????,??,???????,??????,??????????????????”????,???????????????,??????????;???????????????????;???,??????????,???????
CAR-T????
???????????????CAR-T?????,???????:CAR-T???????????????????????CAR-T???
?????CAR-T?????,???????,??,???CAR-T???,????????????????????????????,????????????????
?,???????????“??????????”??,?????????,????????,?“????”????????????????????????????????????,???,??????????CAR-T???????????????,?????????????????????,??????????
????,CAR-T?????,?????????????DRG/DIP????,?“??????????”??????,???????“?????????????????????,????????????????????,???”???
???????,“??”?????????????,????????????????????“??????????????”??????????????,????????CAR-T????
“?????CAR-T?????????????????????50%~70%?????????”?????????CAR-T????????????????
????????,????????????????????CAR-T???????????,??????????,?????????????,??CAR-T?????4.3????????????,???????CAR-T??????????????????????????????????????
??????????,?????,CAR-T???????,????,???CAR-T????????
???CAR-T??????????,????????PD-1????????????,CAR-T????????,?????????,??,????????,?????????????????,???????,?????????????????????????
????????????????????2024???????????3???????1???CAR-T?????????????????(??????????????)???????????,??????? CAR-T????11 ???????????????,???????6??
??????????“2025-2030??(CGT)??????”??,????????,??CAR-T???????,2023???????20%,??????????184??,???168?????????????????????????
??????????????????????,????????????,?????????????CAR-T????“??????????????????”????
???????????????,2032????????CAR-T??????????????885.2?????????????????????,???“?????,??”(????????? ??????????????:???) ?????????????????????:???????