??????????,????CAR-T(???T????????????????)??????????????“????????”??????

CAR-T?????????????????,??:????,?“??????????”????????“????,?????”????????????,????????????,?????????

?????“????????”,?????

?????? 11 ??,???????,99.9????????????CAR-T???????,???????CAR-T??????????????1???????,????????CAR-T???????????????,????????????,??120????CAR-T???????60????

8??????????????????,??,???????????CAR-T?????????????6???????CAR-T??“???????”?,????????????,?????“????”?????,?????????????????????????“??????????????????”???????????????“???????”???????,???????????

???,??????????:??????????“????????????????????????”????????“????”????,???CAR-T?????????“?”????,??????????

?,??????“?????”????????????????,????????????????,CAR-T????????,???

??

?????70%????????60%??????,??????“??”?????41.3%?

????????????????,?,?????????????“??????????”????????????????????????????????????????,????????,??????“??????”,????????,?????????????????????

?CAR-T???????????????,“??”????????

???????????????®(?????)??,??2021???,??????????????????????????,????????,????????????

?????????“??”??,?????8??????????????????,????,??????/???????????,??????????????????????,??4???????CAR-T?????

?,??????????,???????????29??,???30?????,??????99.9?????????/????????~120??/??????????CAR-T?,????????????????

?????????????????4????????????????????,????????????????????????,?????????????????????,?????,???????????????????,?????CAR-T???????????????,???????CAR-T????????????????????????

???????,CAR-T????????,??????????????????????“??????”,?????????“???????????”?????,??????CAR-T???????????????????????,??

????,??????????????????,???????????

??????????«??»??,???????,???????“????????????”???????????????,??????????“??”?????,?????????????

?????????,CAR-T??????????????,??????:

????????????????,CAR-T??100????????,??????????????????????????“?????????????????”???2023?????????????????1.9??????????(19.4%)????????????????1.7?????????(25.3%),??????????,??????????“???????????????”???????????????????????,??“????????30????”????????????????????,????“???”?

??,?????????,????????,??,????????????????????????CAR-T?????????,???????????,????????????????,?????????,???????“????????????????”????

??????????????

???,???CAR-T???????,??????“?????,???”??????,?????????????“??”????????????

?????????,???????????????????????????????,????????????CAR-T??????,???????

??1?,????????????????“????????????”,???????????,?60????????????

????????2024?????????????????,????????????????????????,????????????????????????????,????????????????????????????????,??????????,????????????

???????????????????:“??????,??????????????,????”

??,?????????????,???,????????“???????????”,?,???,??????,????,?,????????,??????

??,??“1+3+N”????,??“N”??,??????????????????,????????“N”???????,????????????

?????,????

?????????????????“????”?????????????????????,??????????????,???????

?????????????????????,????????????????????,?,???????,???

“?????????,?300??????????????,???????CAR-T??????,CAR-T???????????,??????????,??????,??????‘???????????’???????,????????,??,?????????????,?????????????????????,????????????????????,????????????;??????????,??????????????????????????????????,??????????,?‘??????????????’?”?????

????????????“??”?????????????????????,???????????????????,???????????????????

???????????,????????????,????????????????????????????,????,???????????????,???50????????????????,???,???,????????????????????????????????

?????????????????,????????,??????????,??????????????????????????????????????????????????????????????????????,?????

??????,??????????????????????,????????????????????????,??????????????“???”,???,????????????????????????????????????,?????????????????????

?????,??????????????????????????,???????????,??????????????????????

??“?????????”,???????,??????????

??????????100??????CAR-T??,??,????????????????,??????????????????????????,????????????????CAR-T????????????????26?????????,??????????,??4????,???????????????

???“???????????????????”,????????????????????,???????,??????????????????????

“??????????????100????,?????????????CAR-T?????,???????????????,???????,?????????????????????,??????????”??????,??????????????????,???;?????????????;?,???????????,??????

CAR-T??

????CAR-T??,??:CAR-T?????CAR-T????

???????CAR-T???????,?,??,??CAR-T???,??????????????????????,?????????

??????,????“???????????”???????,??????????,???????????,?“??”?????????????????,???,????????????????????CAR-T??,????????,????????

???????,CAR-T??,??????????DRG/DIP???,???????????????“???????????????????????????”???????,?????????????“???????????????????????????,???????,???????”??????

?????????????,“??”?????????????????,??“??????????????????”????????????????????????????,?????CAR-T???????????

“???CAR-T???????????50%~70%???????”?????CAR-T???

??????????,??????CAR-T????????????????????????,?????????????????????????????????????????????,??????????????,????CAR-T????4.3????,?????????????CAR-T????

??,???????????????????,CAR-T???????,???????????????????????????,?????????????CAR-T????????????????

?????????????????????CAR-T??,??????????????PD-1???,CAR-T????????????,????,???,??,????????????,????????????,??

?????2024????????3??????????1??????????????CAR-T??????(??????????)??,?????? CAR-T?????????11 ??,??6??????????

???????????“2025-2030??????????(CGT)????”???????,??,??????????????????????????CAR-T????,2023??????????20%,???????????184???????,????168????????????????????????????????

???????????,????,????????CAR-T????“??”???????????????????

??,2032??????CAR-T???885.2??????????????????,??????????????????????“???,????????”(????????????? ??????????:???) ??:??????????? “????????”????

?? ?????|???????,“??”???????

????:1?????????:?????????600

2?????????zj

3?????????

4?????QQ?

5??????

??????????,????CAR-T(???T????????????????)??????????????“????????”??????

CAR-T?????????????????,??:????,?“??????????”????????“????,?????”????????????,????????????,?????????

?????“????????”,?????

?????? 11 ??,???????,99.9????????????CAR-T???????,???????CAR-T??????????????1???????,????????CAR-T???????????????,????????????,??120????CAR-T???????60????

8??????????????????,??,???????????CAR-T?????????????6???????CAR-T??“???????”?,????????????,?????“????”?????,?????????????????????????“??????????????????”???????????????“???????”???????,???????????

???,??????????:??????????“????????????????????????”????????“????”????,???CAR-T?????????“?”????,??????????

?,??????“?????”????????????????,????????????????,CAR-T????????,???

??

?????70%????????60%??????,??????“??”?????41.3%?

????????????????,?,?????????????“??????????”????????????????????????????????????????,????????,??????“??????”,????????,?????????????????????

?CAR-T???????????????,“??”????????

???????????????®(?????)??,??2021???,??????????????????????????,????????,????????????

?????????“??”??,?????8??????????????????,????,??????/???????????,??????????????????????,??4???????CAR-T?????

?,??????????,???????????29??,???30?????,??????99.9?????????/????????~120??/??????????CAR-T?,????????????????

?????????????????4????????????????????,????????????????????????,?????????????????????,?????,???????????????????,?????CAR-T???????????????,???????CAR-T????????????????????????

???????,CAR-T????????,??????????????????????“??????”,?????????“???????????”?????,??????CAR-T???????????????????????,??

????,??????????????????,???????????

??????????«??»??,???????,???????“????????????”???????????????,??????????“??”?????,?????????????

?????????,CAR-T??????????????,??????:

????????????????,CAR-T??100????????,??????????????????????????“?????????????????”???2023?????????????????1.9??????????(19.4%)????????????????1.7?????????(25.3%),??????????,??????????“???????????????”???????????????????????,??“????????30????”????????????????????,????“???”?

??,?????????,????????,??,????????????????????????CAR-T?????????,???????????,????????????????,?????????,???????“????????????????”????

??????????????

???,???CAR-T???????,??????“?????,???”??????,?????????????“??”????????????

?????????,???????????????????????????????,????????????CAR-T??????,???????

??1?,????????????????“????????????”,???????????,?60????????????

????????2024?????????????????,????????????????????????,????????????????????????????,????????????????????????????????,??????????,????????????

???????????????????:“??????,??????????????,????”

??,?????????????,???,????????“???????????”,?,???,??????,????,?,????????,??????

??,??“1+3+N”????,??“N”??,??????????????????,????????“N”???????,????????????

?????,????

?????????????????“????”?????????????????????,??????????????,???????

?????????????????????,????????????????????,?,???????,???

“?????????,?300??????????????,???????CAR-T??????,CAR-T???????????,??????????,??????,??????‘???????????’???????,????????,??,?????????????,?????????????????????,????????????????????,????????????;??????????,??????????????????????????????????,??????????,?‘??????????????’?”?????

????????????“??”?????????????????????,???????????????????,???????????????????

???????????,????????????,????????????????????????????,????,???????????????,???50????????????????,???,???,????????????????????????????????

?????????????????,????????,??????????,??????????????????????????????????????????????????????????????????????,?????

??????,??????????????????????,????????????????????????,??????????????“???”,???,????????????????????????????????????,?????????????????????

?????,??????????????????????????,???????????,??????????????????????

??“?????????”,???????,??????????

??????????100??????CAR-T??,??,????????????????,??????????????????????????,????????????????CAR-T????????????????26?????????,??????????,??4????,???????????????

???“???????????????????”,????????????????????,???????,??????????????????????

“??????????????100????,?????????????CAR-T?????,???????????????,???????,?????????????????????,??????????”??????,??????????????????,???;?????????????;?,???????????,??????

CAR-T??

????CAR-T??,??:CAR-T?????CAR-T????

???????CAR-T???????,?,??,??CAR-T???,??????????????????????,?????????

??????,????“???????????”???????,??????????,???????????,?“??”?????????????????,???,????????????????????CAR-T??,????????,????????

???????,CAR-T??,??????????DRG/DIP???,???????????????“???????????????????????????”???????,?????????????“???????????????????????????,???????,???????”??????

?????????????,“??”?????????????????,??“??????????????????”????????????????????????????,?????CAR-T???????????

“???CAR-T???????????50%~70%???????”?????CAR-T???

??????????,??????CAR-T????????????????????????,?????????????????????????????????????????????,??????????????,????CAR-T????4.3????,?????????????CAR-T????

??,???????????????????,CAR-T???????,???????????????????????????,?????????????CAR-T????????????????

?????????????????????CAR-T??,??????????????PD-1???,CAR-T????????????,????,???,??,????????????,????????????,??

?????2024????????3??????????1??????????????CAR-T??????(??????????)??,?????? CAR-T?????????11 ??,??6??????????

???????????“2025-2030??????????(CGT)????”???????,??,??????????????????????????CAR-T????,2023??????????20%,???????????184???????,????168????????????????????????????????

???????????,????,????????CAR-T????“??”???????????????????

??,2032??????CAR-T???885.2??????????????????,??????????????????????“???,????????”(????????????? ??????????:???) ??:???????????