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???1??14??????????????????????? (?????? ??????????????)“??????????,??,??????????????????”???14????????????????,“??????????(ADC)???,?????????????,??????????????????,????????????”

??????,??????,?????????????????,??????????????,????,“???????????????”??????????

???????????????,????????????????????????????,????,???:?????????????????,??,???????????????20%?????30%??????????,?????????????????:??“???,????????????”??,???????,??????

??????,????????????,???:??????,????????????????,?????????????????,????????????????????????????????????????????????????,??????,??????,??????????,????????,?????????????????,?,??

??,?????????-2(HER2)?????,????“HER2??”??“HER2??????”?????????????????????,??HER2????,??????HER2????????,HER2???

??,???????,HER2???????20%????????????????????,?????????????????,??????????????????????????????????,ADC?????“HER2???????????HER2???????????,???????????????ADC?????????????,????????????????????,??????HER2??,ADC?,???????‘1+1>2’???????,???????????”

HER2????45%?????????????55%??????????????,?????????????HER2???????????????,?????????HER2????????,????????HER2???????:“?????????????????HER2?,???????ADC???HER2?????????????????????????????HER2?????????????,?????????????,?HER2?????????????????,?????,???????”

??????????????????,ADC????????????,??????????,ADC???????????;????????????

??,??2017???????????????????,??,??????????,????????????????,????????:“??????,?????,???????”

?????????????,????,?,?,?????,??????:??????????????????????????????????????????????????????,??????????????????????,??????40????????????????B??????????????????????,????????????,???:????????????40??????,????????????????,???????(??????) ??????????:????????????????

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