????????? ??????????????

????:???????????:????

????????????8?22???????????? (?? ?)“KRAS????????????????????????,??‘????’????KRAS G12C??????????”?????????

???????????????????????????????21????,???????????,???1????(??:??)???????????,??????????(KRAS)G12C????????????????????(NSCLC)??,??????

??????????????,?KRAS G12C???????????,??

?????????,?????????,2022?????,??????106.1?????????,??????????????????????????????80%85%,???Kirsten???????????????(KRAS)?????????????????,????????????????????????????????????????????????KRAS G12C??3%,??????2.7????

??????KRAS????“??????”,???,?????????????????????,???????????40??,???????????,??????????

??,???????????????????????????KRAS G12C????????????,????????????????(??) ??????:??????