????????????????????????11????????????10??????????(???? ???)?????????????????????113?????????????????????????????????;???14.1?????????????????????????????????????????;??????????????:???????;?FDA????;????;??????????????KRAS G12C??????????;???????????;??????……??11?????????????????4??????????-11?10?,?????

??????????

????

11??5?????????,??????????????????????,???????????????????????????,??“??”????????????????????????????????????“???????????”?????????????,????????????????????,????????????????????,???????????????????????

??????????????????????????:?????????113??????????????

11??7?,?,???40?????????,????????“???????”??????????????????30??????????????,??????,113?????????????????????«????(ICD-11)»???????????,???????????????????????,?,??????????ISO/TC249,????113?????????????

???????

???????????????????????????14.1?????????

11??????7????,???App???????????????,????,?,????2.1?14.1??,?????????571%?????????2022??4??,???????,?????????????????????????????????????????(??????)??????????,???????????????????????????(600436)??

?????:??????????

11?????8??,???????????????,???????????????HRS-2189???????????????????HRS-5041 ???HRS-1358??HRS-8080?????????SHR-8068???????????????HRS-620 ???«??????»,???????

?????????????FDA??

11?8?,???,??????(FDA)?????????????????(New Drug Application,NDA),????????????,???? FDA ?,????????????????????????(EGFR)20 ????????(Exon20ins)??????????(NSCLC)??????????????????? FDA ??

?????

?

11????6?,?????????,????®(??????????????????)?,?????????????????(ANCA)???????(?[GPA]????????????????????????[MPA])??????????????

????????????KRAS G12C????????????

11?9??????,??,???????????????????KRAS G12C????(???????????????????“?”)????,????????????KRAS G12C?????????????????????????????????(NSCLC)????,?????????????????,????????1???????,?5???,??????????????????????6???KRAS G12C?????????????,??????KRAS G12C?????????????????

???????????????????

??????????????????????

11??????7??????????????????,???????????«???????????????»?«???????????»????,??,????????????????????,????????«???????»«???»????????,??????????,????????????????????????????,???????????,??????????????????????????????????????,??

??????????????

?11?5??????????

??Aradhana Sarin???????,????????????,?,?????

?,??????????????????,???????????????????????????,?????????????(??????????????????????) ???????????????????????????:??????????? “???????????”????

?? ??????????????|??????;???????????????

????:1????????????:??????????????

2????????

3???????

4?????????

5????????

????????????????????????11????????????10??????????(???? ???)?????????????????????113?????????????????????????????????;???14.1?????????????????????????????????????????;??????????????:???????;?FDA????;????;??????????????KRAS G12C??????????;???????????;??????……??11?????????????????4??????????-11?10?,?????

??????????

????

11??5?????????,??????????????????????,???????????????????????????,??“??”????????????????????????????????????“???????????”?????????????,????????????????????,????????????????????,???????????????????????

??????????????????????????:?????????113??????????????

11??7?,?,???40?????????,????????“???????”??????????????????30??????????????,??????,113?????????????????????«????(ICD-11)»???????????,???????????????????????,?,??????????ISO/TC249,????113?????????????

???????

???????????????????????????14.1?????????

11??????7????,???App???????????????,????,?,????2.1?14.1??,?????????571%?????????2022??4??,???????,?????????????????????????????????????????(??????)??????????,???????????????????????????(600436)??

?????:??????????

11?????8??,???????????????,???????????????HRS-2189???????????????????HRS-5041 ???HRS-1358??HRS-8080?????????SHR-8068???????????????HRS-620 ???«??????»,???????

?????????????FDA??

11?8?,???,??????(FDA)?????????????????(New Drug Application,NDA),????????????,???? FDA ?,????????????????????????(EGFR)20 ????????(Exon20ins)??????????(NSCLC)??????????????????? FDA ??

?????

?

11????6?,?????????,????®(??????????????????)?,?????????????????(ANCA)???????(?[GPA]????????????????????????[MPA])??????????????

????????????KRAS G12C????????????

11?9??????,??,???????????????????KRAS G12C????(???????????????????“?”)????,????????????KRAS G12C?????????????????????????????????(NSCLC)????,?????????????????,????????1???????,?5???,??????????????????????6???KRAS G12C?????????????,??????KRAS G12C?????????????????

???????????????????

??????????????????????

11??????7??????????????????,???????????«???????????????»?«???????????»????,??,????????????????????,????????«???????»«???»????????,??????????,????????????????????????????,???????????,??????????????????????????????????????,??

??????????????

?11?5??????????

??Aradhana Sarin???????,????????????,?,?????

?,??????????????????,???????????????????????????,?????????????(??????????????????????) ???????????????????????????:???????????