????:1???????:???

2?????????

3???????

4???????500?4???

5?????300???

?????8?25????(?)?“????????”,??????????????;?????????,?????Castor??40%???????????;??????;????0?????????????????????????????,????……????8??19???????-25?,??????????????????

????

????????????:6???

8???????????????????????21?????,??,?????????????????????????????????????????6??????

??,????????????,??????????,???6?????????,??????????????????????????????????????????????????????????????????,???????????????????????????????????????????????????????,?????????,???????,???,???

??,????????????????????????????????????????????????????????????????????,??????????????,??????3-4????,????6???????????????????;?????????????????????????3???????????????12???????????

???Castor????

8??19????????????????,?Castor????(???????????????????“Castor??”)???Castor??????????(200mm??????????????)??????????5?????,?12??????????????????????????,??????????????,????,????????

8???????????24????,???????,??????Castor??7?????????????

????

??

8????????????19??,???????????????,?????????????????????????????,???????????????,?????????7?21?????,????100??,?2270??,??460???????

???

8?????20???????????,?????????????,????????12.10?????,?5.79??????

????2.54?????

?????,????8???23???????????????8????9???????,????,??,??,?,???????????????????2.54???????,??0?????

????????????????????

????

?(???????????????)????,??????(????) ??,????

???? ??

8?19?????????,???????????????,?(AstraZeneca)???????????????????????????,??(benralizumab)????IL-5????????,???FDA????????????????????????

?????????????®??????????????,????????KRAS G12C??????

8???????21??????????????,?1????(?:???????????)???????,??(KRAS)G12C???????????????(NSCLC)??????????????,????????KRAS????????????

????????????????????????????????????

?3.25?

8??????????????20?????????,????????2024????????,??177.97??????????????????????????????,????17.70%;???3.25??,???????40.19%?????10?0.2174???????????(??),?????3252.04??

??????10.01?????????

8?21?,????????????,2024?????????????247.57??????,????2.55%;?10.01??,??????1.62%?

??????4.89?????????

8?????????21??????????,?,2024???????????,???????21.73???,??????????8.02%;??4.89?,????8.66%???2024??????10?5?????????????(?)?

?

8????21?,??????????????2024?????????,???????16.57?,??13.53%;??11.21??,?????16.35%??,???????,?????

????34.32??????

8??21????????????,?????????2024???????,???????????????????136.01???,????21.78%;????34.32?,??????48.67%;?34.90?,?????????????????????92.94%,??50.69%?

????????

8??????????22????,???????2024??,????????????,?????13.66????????,????????????67.19%;??2.6???????????????????????????????,???????84.7%?

???????????????28.11???????????????

8?23????,????2024??????????,???????28.11??,??????????????????????6.30????11.02%;??7.43???,?51.92%?(????) ???????????????????????:????????????????