????????“????+????” ??????“?”?????

????:????????:?????????????

???10??????24???????????(??????????? ??)??????????????15%-20%,??????????????????????????,????????????????????,???“?”???

????????????????“??(????????????????)”,???????“????????”????????????,????????????????(“?????????????????”?????????“?????”?????“????????”),????????????10%????“?????”??????????

?????«??????????????????????????????????»(The BMJ)24?????????????????(???????????)

??????????????????«???????»(The BMJ)24??????????????????????????

?????,???????,??,??????????????????,?????,???????????????????,?????????,???

?,????“????????????????????????”?????????,?????????????????????????????,?????

2015????????????????????,?????????5???????RNA?????????????(???????????????“??”),????????????????

?,??,????????(????????)?????????6????????,??????????????????????????????????????????????????????,??????????1:1?????,???????????????45????????????,?????3??90.9%,???80.6%,????????49%;??3?????92.6%,????????????????????83.2%,???????50%??????

??,????10%????????????????,??????????????

????????,??????????????????????,????????????????????????????????????????????(???????????)

??:?????????????????