????????????????T2T??????

?2???????8?????? (????? ??)8?????????????,????????????:??????,?????????????????????T2T?????--????????????????,?????“?????????????????????”??????

??,??????????,??,??,????????,?????????,??????????????ONT?Hi-C???,????????T2T??????,?“??”,??????????????????

??:???????????????????????????????,??????2.66Gb??????,?N50????????Scrofa11.1?????????,??????????,???1-12?????????????????????X???????,???13-18?????????????,???

???????????:???????????????T2T????????????????????????????,?????,?????194,234???????????????(SV),??????SV?????????,????

??:?????T2T??????????????????,?????????89????????????????????,???????????????????????TPT1???????????????????????????SV?????????????????RNA?????????????,??????????17??????????????????????????????

??????????:???????????????????????SV????????,???????????????????????(GS)?????????,6????????????????????5????????????????70%,????88%??????????,80%?????“SNP+SV”???????????????,???????????2%-4%????,??????CL3????????????SV????,??????????????????

????,?????????:???????????????;SV????????????????,?????,???;???????,????????,????????????(??) ??????????:?????